Keeping up with 21st century viruses has proven to be a tall task. Leveraging genomics, bioinformatics and synthetic genomics expertise at JCVI, coupled with conventional scientific approaches, we are committed to developing better vaccines and therapeutics, by gaining a deeper understanding of how viruses cause disease.

Genomics of Chikungunya Virus

Sequencing Chikungunya virus genomes isolated from the Western hemisphere during the 2014 Caribbean outbreak

Genomics of Zika Virus

Investigating the genomics of Zika virus throughout the Americas

Genomics of Rotavirus

Sequencing Rotavirus genomes isolated from around the world

Genomics of West Nile Virus

Sequencing West Nile virus genomes isolated in the United States

Genomics of Respiratory Syncytial Virus

Sequencing clinical isolates of Respiratory Syncytial Virus in various locations

Genomics of Influenza A and Influenza B Viruses

Sequencing Influenza genomes isolated from various hosts and locations

Genomics of Eastern Equine Encephalitis Virus

Elucidating transmission of EEEV in the United States

Viral Synthetic Genomics to Engineer Large dsDNA Viruses

Rapid engineering of large dsDNA viruses using synthetic genomics assembly tools.

Assembly of HSV-1

Use of cutting-edge synthetic genomics technology to revolutionize the study of herpesvirus biology.

A Synthetic Human Cytomegalovirus Vaccine Platform

Generation of an HCMV low passage clinical isolate using synthetic genomics.

Chemical & Engineering News

Can CRISPR help stop African Swine Fever?

Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.

Collaborator Release

New LongCOVID research launched by PolyBio’s global consortium of scientists

Funding will deepen research on the persistence of the SARS-CoV-2 virus in LongCOVID patients and launch new clinical trials

Press Release

J. Craig Venter Institute scientists awarded five-year, $5.7M grant from NIH to develop phage treatment

Phage research accelerates with the rise of antibiotic resistance to address increasingly prevalent and difficult to treat bacterial infections

Collaborator Release

Family resemblance: How T cells could fight many coronaviruses at once

LJI researchers work to head off future pandemics by uncovering key similarities between SARS-CoV-2 and common cold coronaviruses

Collaborator Release

Scientists aim to develop vaccine against all deadly coronaviruses

$8 million NIH grant supports effort to avert next pandemic


Top scientists join forces to study leading theory behind long COVID

Several JCVI scientists will be contributing to the newly launched Long Covid Research Initiative — a collaboration of researchers, clinicians, and patients working to rapidly study and treat long Covid.

Press Release

Omicron and Beta variants evade antibodies elicited by vaccines and previous infections, but boosters help

Pregnancy also contributes to a reduced COVID-19 antibody response


SARS-CoV-2 Mutation Tracking

Press Release

J. Craig Venter Institute Scientists to Investigate Role of Opioid Abuse in HIV and HIV-Associated Neurocognitive Disorders Pathogenesis through $4.7M NIDA Grant

Study aims to identify candidate molecules to regulate HIV infection in the central nervous system in patients abusing opioids

Press Release

Maintaining a Healthy Upper Respiratory Tract Microbiome May Help Prevent Secondary Infections in Influenza A Patients

An influenza-impacted upper respiratory tract microbiome may invite opportunistic bacterial pathogens


Fighting Back Against Flu

Collaborator Release

Past encounters with the flu shape vaccine response

Immune history influences vaccine effectiveness, interacting with other potential problems arising from the manufacturing process