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J. Craig Venter Institute-led Team Awarded 5-year, $10.7 M Grant from U.S. Department of Energy to Optimize Metabolic Networks in Diatoms, Enabling Next-Generation Biofuels and Bioproducts
Research builds on a series of recent landmark studies, at JCVI, which have led to transformative new methodology for synthetic biology and functional genomics
Don't blame your genes for your toothache, twin study shows
For the first time, investigators have looked at the role that genes and the oral microbiome play in the formation of cavities and have found that your mother was right: The condition of your teeth depends on your dietary and oral hygiene habits. The study appears September 13 in Cell Host & Microbe.
Precision medicine opens the door to scientific wellness preventive approaches to suicide
Researchers have developed a more precise way of diagnosing suicide risk, by developing blood tests that work in everybody, as well as more personalized blood tests for different subtypes of suicidality that they have newly identified, and for different psychiatric high-risk groups.
Defining Standards for Genomes from Uncultivated Microorganisms
Expanding minimum information standards for single-cell genomics, metagenomics datasets.
Energy Department Announces up to $8 Million to Enable Breakthroughs in Algae-Based Biofuels
Scripps Institution of Oceanography, and the J. Craig Venter Institute, Global Algae Innovations will deliver a tool for low cost, rapid analysis of pond microbiota, gather data on the impacts of pond ecology, and develop new cultivation methods that utilize this information to achieve greater algal productivity.
Scientists from J. Craig Venter Institute and Scripps Institution of Oceanography Publish Study Describing Function and Mechanisms of Diatom Centromeres
Research provides basic but essential information about how diatom chromosomes are replicated and maintained
Digital-to-Biological Converter for On-Demand Production of Biologics Developed by Synthetic Genomics, Inc.
The first fully automated machine to convert digital code into functional biologics without human intervention creates entirely new avenues for precision medicine
Intestinal Fungi Worsen Alcoholic Liver Disease
Reducing intestinal fungi slowed disease progression in mice
JCVI President, Karen Nelson Elected to National Academy of Sciences
Stool Microbes Predict Advanced Liver Disease
Proof-of-concept study suggests a noninvasive test for specific microbial population patterns could be used to detect advanced nonalcoholic fatty liver disease
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My journey begins: heading to the Puerto Rico Trench in search of deep-sea plastic
Editor’s note JCVI Staff Scientist Erin Garza, Ph.D., was selected to embark on a unique research expedition aboard the HOV Alvin submersible, a crewed deep-ocean research vessel owned by the United States Navy and operated by the Woods Hole Oceanographic Institution, that has brought...
Celebrating pioneers in science and medicine this Black History Month
Happy Black History Month! At JCVI, we believe in the importance of celebrating scientific trailblazers, particularly those who made groundbreaking advancements all while overcoming overt racism. Here, we have highlighted the stories and achievements of some of the most accomplished Black...
Eleven female scientists whose research changed the world
Today is Women’s Equality Day and to celebrate, we are highlighting accomplishments made by women in science and technology. While these scientists were influential in advancing their fields and championing the fair treatment of women in science, currently women only make up 28% of the...
Complete Genome Sequence of Strain JB001, a Member of Saccharibacteria Clade G6
The complexity and diversity of the microbial world was not fully understood until sequencing technology allowed us to study microbes without growing them in the lab. An important family of bacteria, Saccharibacteria (formerly called TM7), is one of the many bacteria of interest which were...
Scientific Pioneers
JCVI recognizes trailblazers in scientific history, particularly those who made advancements all while surpassing gender, ethnic, and other societal barriers, creating opportunity for the next generation of scientists. These historical figures not only helped advance our understanding of human...
Women’s History Month: Tu Youyou
Tu Youyou is a Chinese pharmaceutical chemist whose unique training in the classification of medical plants and their active ingredients resulted in a discovery that has led to the survival and improved health of millions of people. In 1967, at the height of the Vietnam War, malaria spread by...
SARS-CoV-2 Mutation Tracking
The Bacterial Viral Bioinformatic Resource Center (BV-BRC) is proud to introduce a new resource with the goal of providing live tracking of SARS-CoV-2 mutations. This real-time resource will provide regular reports focused on “Variants and Lineages of Concern” (VoCs/LoCs), and will serve as an early warning system for variants that are increasing in frequency in specific geographical locations.
JCVI Scientists and Interns Dramatically Trim Proteome Analysis Costs with New Lab-on-a-Filter Process
Through a happy accident and a keen mind, JCVI intern Rodrigo Eguez realized scientists might be able to pack their own filters rather than rely on those produced commercially at a significant cost savings. While playing around in the laboratory, he inadvertently disassembled a filter device...
Unique Antibody Pattern Discovered in COVID-19 ICU Patients May Be Key to Predicting Severe Outcomes
While news of promising COVID-19 vaccine trials is heartening, the fight to control infection rates and develop effective treatments will be an ongoing challenge for science for years to come. Gene Tan, PhD and his collaborators are working on identifying...
Synthetic Cell-Powered Lotion to Manage Type 1 Diabetes
Early last year we first talked about how researchers Yo Suzuki, PhD, and John Glass, PhD at JCVI set out to eliminate the need for type 1 diabetes (T1D) patients to receive insulin injections to manage blood glucose levels through a novel approach: developing a bacterial replacement for beta...
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Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
Scientists Create the Smallest-Ever Moving Cell
Just two genes get tiny synthetic cells moving, offering clues to life’s evolution.
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