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Climate change and iron availability may drastically alter algae blooms in the Southern Ocean, trapping vast nutrients
Shifts in diatom population may have profound effects on global nutrient distribution and carbon cycling
New wiki on salivary proteins may transform diagnostic testing and personalized medicine
Database curates info on inner workings of saliva, an attractive tool for noninvasive diagnostics and precision medicine
National Academy of Sciences launches new open access journal, PNAS Nexus, in partnership with Oxford University Press; Karen Nelson to serve as inaugural editor-in-chief
Genes necessary for cell division in modern bacterial cells identified
Discovery may help shape understanding of primitive cell division
Scientists find evidence that novel coronavirus infects the mouth’s cells
NIH-funded findings point to a role for saliva in SARS-CoV-2 transmission.
Scientists map how iron, a critical mineral for survival, is processed by algae, a cornerstone of the ocean food web
Nearly forty proteins identified in the intracellular process, helping to build a conceptual overview of how iron is allocated within diatom cells
J. Craig Venter Institute Scientists to Investigate Role of Opioid Abuse in HIV and HIV-Associated Neurocognitive Disorders Pathogenesis through $4.7M NIDA Grant
Study aims to identify candidate molecules to regulate HIV infection in the central nervous system in patients abusing opioids
Influenza A Virus Discovered in Heart Muscle Tissue Causing Damage Long After It Has Cleared from the Lungs
Strategies to inhibit necrotic cell death or to prevent mitochondrial damage should be pursued as possible therapies to reduce cardiac damage during influenza infections
Hamilton O. Smith, M.D., Synthetic Biology Pioneer and Nobel Laureate, to Step Down from Daily Duties at J. Craig Venter Institute
Dr. Smith will maintain advisory role as professor emeritus
Scientists set a path for field trials of gene drive organisms
As genetically engineered organisms ramp up, a multidisciplinary coalition offers a framework for ethical, socially engaged and transparent field practices
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My journey begins: heading to the Puerto Rico Trench in search of deep-sea plastic
Editor’s note JCVI Staff Scientist Erin Garza, Ph.D., was selected to embark on a unique research expedition aboard the HOV Alvin submersible, a crewed deep-ocean research vessel owned by the United States Navy and operated by the Woods Hole Oceanographic Institution, that has brought...
Celebrating pioneers in science and medicine this Black History Month
Happy Black History Month! At JCVI, we believe in the importance of celebrating scientific trailblazers, particularly those who made groundbreaking advancements all while overcoming overt racism. Here, we have highlighted the stories and achievements of some of the most accomplished Black...
Eleven female scientists whose research changed the world
Today is Women’s Equality Day and to celebrate, we are highlighting accomplishments made by women in science and technology. While these scientists were influential in advancing their fields and championing the fair treatment of women in science, currently women only make up 28% of the...
Complete Genome Sequence of Strain JB001, a Member of Saccharibacteria Clade G6
The complexity and diversity of the microbial world was not fully understood until sequencing technology allowed us to study microbes without growing them in the lab. An important family of bacteria, Saccharibacteria (formerly called TM7), is one of the many bacteria of interest which were...
Scientific Pioneers
JCVI recognizes trailblazers in scientific history, particularly those who made advancements all while surpassing gender, ethnic, and other societal barriers, creating opportunity for the next generation of scientists. These historical figures not only helped advance our understanding of human...
Women’s History Month: Tu Youyou
Tu Youyou is a Chinese pharmaceutical chemist whose unique training in the classification of medical plants and their active ingredients resulted in a discovery that has led to the survival and improved health of millions of people. In 1967, at the height of the Vietnam War, malaria spread by...
SARS-CoV-2 Mutation Tracking
The Bacterial Viral Bioinformatic Resource Center (BV-BRC) is proud to introduce a new resource with the goal of providing live tracking of SARS-CoV-2 mutations. This real-time resource will provide regular reports focused on “Variants and Lineages of Concern” (VoCs/LoCs), and will serve as an early warning system for variants that are increasing in frequency in specific geographical locations.
JCVI Scientists and Interns Dramatically Trim Proteome Analysis Costs with New Lab-on-a-Filter Process
Through a happy accident and a keen mind, JCVI intern Rodrigo Eguez realized scientists might be able to pack their own filters rather than rely on those produced commercially at a significant cost savings. While playing around in the laboratory, he inadvertently disassembled a filter device...
Unique Antibody Pattern Discovered in COVID-19 ICU Patients May Be Key to Predicting Severe Outcomes
While news of promising COVID-19 vaccine trials is heartening, the fight to control infection rates and develop effective treatments will be an ongoing challenge for science for years to come. Gene Tan, PhD and his collaborators are working on identifying...
Synthetic Cell-Powered Lotion to Manage Type 1 Diabetes
Early last year we first talked about how researchers Yo Suzuki, PhD, and John Glass, PhD at JCVI set out to eliminate the need for type 1 diabetes (T1D) patients to receive insulin injections to manage blood glucose levels through a novel approach: developing a bacterial replacement for beta...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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