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Genome Analysis Sheds Light on Mobile DNA's Role in Pathogen's Resistance to Vancomycin
TIGR's sequencing and analysis of the genome of a vancomycin-resistant strain of Enterococcus faecalis has found that nearly a third of the genome consists of "mobile elements" -- segments of DNA that can jump between organisms or their chromosones -- that appear to play an important role in helping the bacterium quickly acquire resistance to drugs.
New Mobile Lab To Bolster Bioscience Education
The nation's newest and largest mobile laboratory, the MdBioLab, will be launched in early February to help Maryland high schools enhance their bioscience education programs. TIGR has partnered with MdBio, Inc., and the University of Maryland Biotechnology Institute to create this innovative non-profit project.
TIGR Offers Genomics Course
Rice Genome Sequence Announced By International Public Consortium
An international sequencing consortium that includes TIGR announced today that scientists have completed the assembly of an advanced, high-quality draft genome sequence of rice and made that data freely available. The sequence is an important new tool for agricultural and nutritional research involving one of the world's most important crops.
U.S.-German Research Consortium Sequences Genome of Versatile Soil Microbe
Pseudomonas putida Has Potential for Use in Bioremediation, Promoting Plant Growth and Fighting Plant Diseases
IBEA Receives $3 Million Dept. of Energy Grant for Synthetic Genome Development
Hamilton Smith, M.D., Nobel Laureate, Named Scientific Director of IBEA
Exploring Bacterial Branches of the Tree of Life
In an ambitious "phylogenomics" project, TIGR scientists have received an NSF grant to use whole genome sequence analysis to better understand the phylogenetic relationships among major bacterial groups.
Announcing the release of two packages useful in the analysis of shotgun sequence assembly data
TIGR evolutionary biologist Jonathan Eisen has been named as one of Esquire magazine's "Best and Brightest" innovators.
TIGR evolutionary biologist Jonathan Eisen has been named as one of Esquire magazine's "Best and Brightest" innovators. The list of 43 "emerging leaders who are reshaping our world" -- including nine scientists -- appears in the magazine's December issue.
TIGR Cracks Genome of Potential Bioremediation Agent
Scientists at TIGR and their collaborators have deciphered the genome sequence of the bacterium Shewanella oneidensis, which has great potential as a bioremediation agent to remove toxic metals such as chromium and uranium from the environment.
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SARS-CoV-2 Mutation Tracking
The Bacterial Viral Bioinformatic Resource Center (BV-BRC) is proud to introduce a new resource with the goal of providing live tracking of SARS-CoV-2 mutations. This real-time resource will provide regular reports focused on “Variants and Lineages of Concern” (VoCs/LoCs), and will serve as an early warning system for variants that are increasing in frequency in specific geographical locations.
JCVI Scientists and Interns Dramatically Trim Proteome Analysis Costs with New Lab-on-a-Filter Process
Through a happy accident and a keen mind, JCVI intern Rodrigo Eguez realized scientists might be able to pack their own filters rather than rely on those produced commercially at a significant cost savings. While playing around in the laboratory, he inadvertently disassembled a filter device...
Unique Antibody Pattern Discovered in COVID-19 ICU Patients May Be Key to Predicting Severe Outcomes
While news of promising COVID-19 vaccine trials is heartening, the fight to control infection rates and develop effective treatments will be an ongoing challenge for science for years to come. Gene Tan, PhD and his collaborators are working on identifying...
Synthetic Cell-Powered Lotion to Manage Type 1 Diabetes
Early last year we first talked about how researchers Yo Suzuki, PhD, and John Glass, PhD at JCVI set out to eliminate the need for type 1 diabetes (T1D) patients to receive insulin injections to manage blood glucose levels through a novel approach: developing a bacterial replacement for beta...
COVID-19 Further Complicating Flu Season
While the world is rightly focused on the ongoing COVID-19 pandemic, it’s important to know that influenza is always a significant public health burden, and the combination of the pandemic and flu season could converge to become a perfect storm of infectious diseases. Influenza causes 3 to...
Sara Josephine Baker
At the beginning of the 20th century, many people remained skeptical of both germ theory and preventative medicine, but pioneering physician Dr. Sara Josephine Baker fought to revolutionize public health and is credited with saving tens of thousands of lives. After studying chemistry and...
JCVI Researchers Help Advance Our Understanding of Ocean Microbes, Developing New Tools and Protocols Through Large-Scale Study
The oceans cover over two-thirds of the Earth’s surface and contain an abundance of life including diverse populations of marine microbes. Studying the genetics, biochemistry and metabolism of these microbes has been one of JCVI’s long standing research initiatives and is...
Online Education Resources to Help With Your New “Normal”
The COVID-19 pandemic has brought many changes to our daily lives and routines, including for many of you the role of an at-home educator for your children due to open-ended school closures. While we also miss directly connecting with students from our community, JCVI remains committed...
Coronavirus Pandemic: Putting Comprehensive Genomic Data in the Hands of Frontline Researchers Worldwide is Paramount
According to the CDC, SARS-CoV-2, the virus causing COVID-19, has now been detected in more than 150 countries/locations internationally. The World Health Organization (WHO) has declared COVID-19 a pandemic, and in the United States it has been declared it a national emergency. As...
Characterization of Bacteria from the International Space Station Drinking Water
From a microbiology perspective, the International Space Station (ISS) is interesting considering its microgravity, increased radiation, low humidity and elevated carbon dioxide levels. Because of its isolation, and unique environment, it is vital to study the microorganisms that thrive there...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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