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Scientists Decipher Genetic Code of Malaria Parasite
In a landmark contribution to the battle against malaria, scientists at TIGR and two other sequencing centers have deciphered the complex genetic code of the Plasmodium falciparum parasite that causes the deadliest form of the disease. In a related paper, a TIGR team also published a comparison of the genome with that of the model rodent malaria parasite, P. yoelii yoelii. And TIGR scientists played a role in sequencing the genome of the malaria-transmitting mosquito, Anophles gambiae.
Fraser Wins Lawrence Award
Secretary of Energy Spencer Abraham announced today that TIGR's president and director, Claire M. Fraser, Ph.D., will receive the E.O. Lawrence Award for her "contributions to genome analysis technology, its extension to the understanding of microbial diversity, and its application to human pathogens."
Towards the $1,000 Genome: "Hot Topic" Added to TIGR Genome Conference
Meeting Kicks Off With Keynote Lecture By Barry Bloom, Dean of Harvard's School of Public Health, Followed by Panel Discussion On New Sequencing Technologies
Genome of Potential Bioterror Agent Sequenced; Highlights Similarities Between Animal, Plant Pathogens
Scientists at TIGR, in collaboration with colleagues at three other research institutes, have determined the complete genomic sequence of Brucella suis, a bacterial pathogen and potential bioterrorism agent that could be targeted against humans or livestock.
Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
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SARS-CoV-2 Mutation Tracking
The Bacterial Viral Bioinformatic Resource Center (BV-BRC) is proud to introduce a new resource with the goal of providing live tracking of SARS-CoV-2 mutations. This real-time resource will provide regular reports focused on “Variants and Lineages of Concern” (VoCs/LoCs), and will serve as an early warning system for variants that are increasing in frequency in specific geographical locations.
JCVI Scientists and Interns Dramatically Trim Proteome Analysis Costs with New Lab-on-a-Filter Process
Through a happy accident and a keen mind, JCVI intern Rodrigo Eguez realized scientists might be able to pack their own filters rather than rely on those produced commercially at a significant cost savings. While playing around in the laboratory, he inadvertently disassembled a filter device...
Unique Antibody Pattern Discovered in COVID-19 ICU Patients May Be Key to Predicting Severe Outcomes
While news of promising COVID-19 vaccine trials is heartening, the fight to control infection rates and develop effective treatments will be an ongoing challenge for science for years to come. Gene Tan, PhD and his collaborators are working on identifying...
Synthetic Cell-Powered Lotion to Manage Type 1 Diabetes
Early last year we first talked about how researchers Yo Suzuki, PhD, and John Glass, PhD at JCVI set out to eliminate the need for type 1 diabetes (T1D) patients to receive insulin injections to manage blood glucose levels through a novel approach: developing a bacterial replacement for beta...
COVID-19 Further Complicating Flu Season
While the world is rightly focused on the ongoing COVID-19 pandemic, it’s important to know that influenza is always a significant public health burden, and the combination of the pandemic and flu season could converge to become a perfect storm of infectious diseases. Influenza causes 3 to...
Sara Josephine Baker
At the beginning of the 20th century, many people remained skeptical of both germ theory and preventative medicine, but pioneering physician Dr. Sara Josephine Baker fought to revolutionize public health and is credited with saving tens of thousands of lives. After studying chemistry and...
JCVI Researchers Help Advance Our Understanding of Ocean Microbes, Developing New Tools and Protocols Through Large-Scale Study
The oceans cover over two-thirds of the Earth’s surface and contain an abundance of life including diverse populations of marine microbes. Studying the genetics, biochemistry and metabolism of these microbes has been one of JCVI’s long standing research initiatives and is...
Online Education Resources to Help With Your New “Normal”
The COVID-19 pandemic has brought many changes to our daily lives and routines, including for many of you the role of an at-home educator for your children due to open-ended school closures. While we also miss directly connecting with students from our community, JCVI remains committed...
Coronavirus Pandemic: Putting Comprehensive Genomic Data in the Hands of Frontline Researchers Worldwide is Paramount
According to the CDC, SARS-CoV-2, the virus causing COVID-19, has now been detected in more than 150 countries/locations internationally. The World Health Organization (WHO) has declared COVID-19 a pandemic, and in the United States it has been declared it a national emergency. As...
Characterization of Bacteria from the International Space Station Drinking Water
From a microbiology perspective, the International Space Station (ISS) is interesting considering its microgravity, increased radiation, low humidity and elevated carbon dioxide levels. Because of its isolation, and unique environment, it is vital to study the microorganisms that thrive there...
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Scientists Create the Smallest-Ever Moving Cell
Just two genes get tiny synthetic cells moving, offering clues to life’s evolution.
From Sequencing to Sailing: Three Decades of Adventure with Craig Venter
In a plenary public appearance at the Molecular and Precision Med TRI-CON event in San Diego, a relaxed Venter reflected on his career highlights, controversies and future priorities for genomic medicine.
Synthesizing life on the planet
What’s the smallest number of genes that cells need to grow and reproduce? Is it possible to synthesize minimal genomes and insert them into cells? What do minimal genomes teach us about life? An interview with John Glass, Ph.D.
Top scientists join forces to study leading theory behind long COVID
Several JCVI scientists will be contributing to the newly launched Long Covid Research Initiative — a collaboration of researchers, clinicians, and patients working to rapidly study and treat long Covid.
Hunting for deep-ocean plastics
Through the Woods Hole Oceanographic Institution, National Deep Submergence Facility, JCVI's Erin Garza, Ph.D. joins a deep sea expedition to search for ocean plastics aboard the HOV Alvin.
A journey to the center of our cells
Biologists are discovering the true nature of cells—and learning to build their own.
Dr. Hend Alqaderi on paving the way for women in science in the GCC
Hend Alqaderi, a JCVI collaborator and mentee to Marcelo Freire receives the L’Oréal-Unesco Women in Science award
Leonardo Da Vinci: New family tree spans 21 generations, 690 years, finds 14 living male descendants
The surprising results of a decade-long investigation by Alessandro Vezzosi and Agnese Sabato provide a strong basis for advancing a project researching Leonardo da Vinci's DNA.
Genome Research Papers on Meningococcal Recombination, Psoriasis Variants in China, More
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