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Scientists Decipher Genome of a Fungus That Causes Life-Threatening Infections in Persons With Impaired Immunity
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Scientists Reveal Molecular Secrets of the Malaria Parasite
Groundbreaking Research Project May Help Boost Vaccine Development
Scientists Decipher Genome of Bacterium that Helps Clean Up Major Groundwater Pollutants
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Genome Comparison of Four Campylobacter Strains Yields New Genetic Markers and Clues to Virulence
In a study that could benefit medical and food-safety research, scientists have used the tools of comparative genomics to find new clues about why some strains of the bacterium Campylobacter - which each year cause more than 400 million cases of gastrointestinal disease - are more virulent than others. The analysis is helping researchers develop more comprehensive detection methods for analyzing human and environmental isolates of the bacteria.
Microbe's Genome Reveals Insights Into Ocean Ecology
Unexpected findings about the genetic makeup of a marine microbe have given scientists a new perspective on how bacteria make a living in the ocean - a view that may prove useful in wider studies of marine ecology. The analysis by TIGR and collaborators of the DNA sequence of Silicibacter pomeroyi found that the metabolic strategies of marine bacterioplankton are more diverse and less conventional than previously thought.
Innovative Metagenomics Strategy Used To Study Oral Microbes
In an innovative new project, TIGR scientists and collaborators are using a metagenomics strategy to explore the complex mix of microbes in the human mouth. The research could help improve the diagnosis and treatment of periodontitis and other oral diseases.
Influenza Genome Sequencing Project Is Launched
TIGR will sequence a large number of human isolates of the influenza virus as part of a landmark influenza genome sequencing project announced Monday by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The project aims to help scientists better understand how flu viruses evolve as they spread through the population.
TIGR and Virginia Tech Sign Memorandum for New Alliance
A new alliance between TIGR and Virginia Tech University is expected to enhance the Institute's computational and experimental capacity as well as enrich the university's basic research in the life sciences. The Memorandum of Understanding, announced Monday, anticipates joint research projects, shared use of related facilities, adjunct faculty appointments, and opportunities for students to participate in research.
TIGR's Fraser, Salzberg Honored As AAAS Fellows
TIGR President Claire M. Fraser and Senior Bioinformatics Director Steven L. Salzberg have been named as Fellows of the American Association for the Advancement of Science (AAAS) in recognition of their contributions to genomics and bioinformatics.
Computational Genomics Conference To Attract Leading Scientists
Comparative genomics, sequence assembly, gene expression analysis and genome annotation are among the hot topics to be discussed at the 7th annual Conference on Computational Genomics, which will be held October 21-24 in Reston, VA. The meeting is jointly sponsored by TIGR and The Jackson Laboratory.
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Back on The Road, Mar Menor to Blanes, Spain
May 7th 2010 After a successful day of sampling in Mar Menor and a great local dinner of lobster paella, Chris and I loaded up the van and got back on the road early Friday morning. We had a 757 kilometer (470 miles) drive ahead of us to arrive in Blanes to meet with a team of collaborators...
The Green Lagoon — Sampling in Albufera de Valencia
During our sampling in Spain last year Chris and I met up with Francisco Rodriguez-Valera. Francisco had some great suggestions for sampling sites and one of them was Albufera de Valencia, a shallow hypertrophic fresh water lagoon, located just 30 minutes drive south of Valencia . When...
Road Sampling Starts in Mar Menor, Spain
Before sampling was to resume on Sorcerer II, a 2 week multiple-site road sampling trip was planned. Chris Dupont arrived in Valencia a day after me, in the next two days we would load up a giant rental van and hit the road. On Wednesday May 5th we drove the 322 kilometers (200 miles) from...
Return to Sorcerer II, The Mediterranean Season
Hello everyone! On May 2nd I flew from San Diego to rejoin Sorcerer II in Valencia Spain. Sorcerer II has been in Spain since our last sample in November, during that time her crew has been very busy upgrading systems and getting the rig certified. Sorcerer II is looking great and is ready for...
Looking for a Few Good Genomes (to sequence)!
The JCVI is one of three centers funded by the National Institutes of Allergy and Infectious Disease (NIAID) to provide sequencing and genotyping services to the infectious disease community. We are continually looking for researchers who would like to have organisms of research interest to...
Influences of trace metals on biological evolution
Scientists show how trace metal chemistry and global changes in oxygen have influenced the evolution of metalloproteins and the Eukaryotes A paper is being published in PNAS this week about how the varying abundance of trace metals in the environment has influenced biological...
JCVI Scientists Recognized by ASM
Drs. Karen E. Nelson and Kenneth H. Nealson are both being recognized by the American Academy of Microbiology (ASM) tomorrow, May 26, 2010. Karen has been elected to Fellowship in the ASM. She is one of seventy-eight new members that have been selected through a peer-review process based on...
Scientist Spotlight: Hamilton O. Smith and Clyde A. Hutchison III
Two of the superstars of science at the helm of the effort to make a synthetic cell (a cell with a completely man-made set of genetic instructions) are Hamilton Smith and Clyde Hutchison, or Ham and Clyde as they are affectionately known to colleagues. Since 2003 when they started working...
Happy DNA Day!
This past March, we had a great time participating in the science programs in San Diego. We ended the month with the SD Science Festival with over 30,000 participants. It was such a busy day - I forgot to take pictures. The venue was Petco Park with hundreds of exhibits and hands-on...
Recomb - Computational Proteomics
I recently attended the Recomb satellite conference on Computational Proteomics (downloads for talk and poster) in San Diego, CA. It was a kind of homecoming for me. I was a computational proteomics researcher at UCSD as a grad student with Vineet Bafna. Many of my classmates were still there,...
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Scientists Create the Smallest-Ever Moving Cell
Just two genes get tiny synthetic cells moving, offering clues to life’s evolution.
From Sequencing to Sailing: Three Decades of Adventure with Craig Venter
In a plenary public appearance at the Molecular and Precision Med TRI-CON event in San Diego, a relaxed Venter reflected on his career highlights, controversies and future priorities for genomic medicine.
Synthesizing life on the planet
What’s the smallest number of genes that cells need to grow and reproduce? Is it possible to synthesize minimal genomes and insert them into cells? What do minimal genomes teach us about life? An interview with John Glass, Ph.D.
Top scientists join forces to study leading theory behind long COVID
Several JCVI scientists will be contributing to the newly launched Long Covid Research Initiative — a collaboration of researchers, clinicians, and patients working to rapidly study and treat long Covid.
Hunting for deep-ocean plastics
Through the Woods Hole Oceanographic Institution, National Deep Submergence Facility, JCVI's Erin Garza, Ph.D. joins a deep sea expedition to search for ocean plastics aboard the HOV Alvin.
A journey to the center of our cells
Biologists are discovering the true nature of cells—and learning to build their own.
Dr. Hend Alqaderi on paving the way for women in science in the GCC
Hend Alqaderi, a JCVI collaborator and mentee to Marcelo Freire receives the L’Oréal-Unesco Women in Science award
Leonardo Da Vinci: New family tree spans 21 generations, 690 years, finds 14 living male descendants
The surprising results of a decade-long investigation by Alessandro Vezzosi and Agnese Sabato provide a strong basis for advancing a project researching Leonardo da Vinci's DNA.
Genome Research Papers on Meningococcal Recombination, Psoriasis Variants in China, More
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