By Ishwar Chandramouliswaran

Looking for a Few Good Genomes (to sequence)!

The JCVI is one of three centers funded by the National Institutes of Allergy and Infectious Disease (NIAID) to provide sequencing and genotyping services to the infectious disease community. We are continually looking for researchers who would like to have organisms of research interest to them sequenced and become a resource for the community. The costs are covered under the NIAID contract to the JCVI Genome Sequencing Center for Infectious Diseases (GSC) and therefore of no cost to the investigators.

The JCVI GSC provides the infectious disease research community with rapid and cost-effective high-quality sequencing services for pathogenic microorganisms including viruses, bacteria, fungi, protozoa, and invertebrate vectors of disease. The center is focused on NIAID Category A-C priority pathogens, related organisms, clinical isolates, closely related species, and microorganisms responsible for emerging and re-emerging infectious diseases and their hosts. Genotyping services are offered by the Center in order to study the variation in host response. The center also offers expertise in pathogen biology with the ultimate goal to use the sequencing and genotyping data to develop new diagnostics, vaccines, and drugs. Data generated from the sequencing and genotyping projects will be released to the scientific community in accordance with the NIAID Data and Reagent Sharing and Release Guidelines.

JCVI has completed many projects to date and over 15 are ongoing or about to start. See here for information about these projects and the collaborators. We are currently in year 2 of our second five year contact and over 70 known publications have resulted from these collaborative efforts.

We particularly encourage multi-collaborator projects that will provide the most impact for the scientific community. The sequencing and genotyping projects to be conducted by center are selected from white paper proposals that can be submitted by investigators worldwide, including academia, not-for-profit organizations, industry, and government. Information about the application process is available here.

Please contact us with questions and for advice about developing a white paper proposal. A JCVI project lead will be assigned to each person/group who submits a white paper to help them with the process and ensure the best chance for success. We look forward to hearing from you!