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Scientists Decipher Genome of a Fungus That Causes Life-Threatening Infections in Persons With Impaired Immunity
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Scientists Reveal Molecular Secrets of the Malaria Parasite
Groundbreaking Research Project May Help Boost Vaccine Development
Scientists Decipher Genome of Bacterium that Helps Clean Up Major Groundwater Pollutants
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Genome Comparison of Four Campylobacter Strains Yields New Genetic Markers and Clues to Virulence
In a study that could benefit medical and food-safety research, scientists have used the tools of comparative genomics to find new clues about why some strains of the bacterium Campylobacter - which each year cause more than 400 million cases of gastrointestinal disease - are more virulent than others. The analysis is helping researchers develop more comprehensive detection methods for analyzing human and environmental isolates of the bacteria.
Microbe's Genome Reveals Insights Into Ocean Ecology
Unexpected findings about the genetic makeup of a marine microbe have given scientists a new perspective on how bacteria make a living in the ocean - a view that may prove useful in wider studies of marine ecology. The analysis by TIGR and collaborators of the DNA sequence of Silicibacter pomeroyi found that the metabolic strategies of marine bacterioplankton are more diverse and less conventional than previously thought.
Innovative Metagenomics Strategy Used To Study Oral Microbes
In an innovative new project, TIGR scientists and collaborators are using a metagenomics strategy to explore the complex mix of microbes in the human mouth. The research could help improve the diagnosis and treatment of periodontitis and other oral diseases.
Influenza Genome Sequencing Project Is Launched
TIGR will sequence a large number of human isolates of the influenza virus as part of a landmark influenza genome sequencing project announced Monday by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The project aims to help scientists better understand how flu viruses evolve as they spread through the population.
TIGR and Virginia Tech Sign Memorandum for New Alliance
A new alliance between TIGR and Virginia Tech University is expected to enhance the Institute's computational and experimental capacity as well as enrich the university's basic research in the life sciences. The Memorandum of Understanding, announced Monday, anticipates joint research projects, shared use of related facilities, adjunct faculty appointments, and opportunities for students to participate in research.
TIGR's Fraser, Salzberg Honored As AAAS Fellows
TIGR President Claire M. Fraser and Senior Bioinformatics Director Steven L. Salzberg have been named as Fellows of the American Association for the Advancement of Science (AAAS) in recognition of their contributions to genomics and bioinformatics.
Computational Genomics Conference To Attract Leading Scientists
Comparative genomics, sequence assembly, gene expression analysis and genome annotation are among the hot topics to be discussed at the 7th annual Conference on Computational Genomics, which will be held October 21-24 in Reston, VA. The meeting is jointly sponsored by TIGR and The Jackson Laboratory.
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USA Science & Engineering Festival
What a great weekend! Thousands of people attended the USA Science and Engineering Festival. There were exhibits and performances for everyone, every age and every interest! The DiscoverGenomics! Mobile Lab was there - Pennsylvania Avenue with several other mobile labs from across...
Second Leg of Greek Sampling
September 19th 2010 After we picked up our samples in Maliakos Gulf and changed Greek collaborators we sailed overnight to Psara Island to collect sample #30 on the sample map. Weather became an issue as we tried to collect samples site #26. The winds were blowing over 30 knots and seas were...
The Start of Greek Sampling and Rough Sampling Conditions!
September 15th 2010 Aegean Sea Map On September 10th we arrived in the northeastern Aegean Sea and docked in the city of Alexandroupolis. We spent a few hours dealing with customs which was not normal for the Mediterranean countries. Turns out that this area is well known for being an...
Tourist in Turkey
September 11th 2010 Our time in Turkey was relatively short, but we saw and learned a lot in that time. Our first stop was in Canakkale, it would have been an uneventful 1 night stop if it wasn’t for this…..Byron Hellespont Bicentenary Swim. This yearly race allows you to swim the 3...
Turkish Transect
September 10th 2010 Tonight we arrived in the Greek town of Alexandroupolis, which is located in northeast Aegean Sea. In the last 3 days we have collected 10 samples from 5 sites; it has been a long couple days! In the last blog I talked about the 2 sample sites in the Black Sea, since then...
Back To Sampling In The Black Sea and Rough Rough Weather
September 9th 2010 Hello everyone! I know it has been a long time since the last post from Sorcerer II. Let me take the time to explain…………..in early August we sailed to Greece. As I have mentioned in the past we have permits with each country to collect samples, these permits have...
Take home message of the 2010 Amebiasis Montreal Meeting: beware of who you kiss…
The Entamoeba community is a small and collegial one. Everyone knows everyone and everyone else wants to collaborate, and learn and do more to tackle down this neglected among neglected diseases. For many, the thought of an amoeba brings to memory Garry Larson’s The Far Side amorphous...
Entamoeba histolytica research presented at the Molecular Parasitology Meeting
Entamoeba histolytica causes invasive intestinal and extraintestinal infections, known as amoebiasis, in about 50 million people and still remains a significant cause of human death in developing countries. However, for unknown reasons, fewer than 10% of E. histolytica infections are...
Virtual Comparative Metagenomics
We have created an open virtualization format (OVF) package of JCVI's Metagenomics Reports (METAREP)- a high performance comparative metagenomics analysis tool. The software runs on a web server, retrieves data from two different database systems and uses R for statistical analysis. The new OVF...
Italy: Sites and Sailing
Saturday July 31st When I last wrote we had finished our 10 day sampling window in Italian waters. On Wednesday July 21st we arrived in Rome the same day Dr. Venter, Heather Kowalski, and Darwin the super boat dog had flown in from the states. We spent 3 days in Rome, most of the time was...
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Craig Venter: 20 years of decoding the human genome
The human genome is 99% decoded, the American geneticist Craig Venter announced two decades ago. What has the deciphering brought us since then?
Scientists in La Jolla Make Progress Understanding New Coronavirus Strain
Gene Drives: New and Improved
As the science advances, policy-makers and regulators need to develop responses that reflect the latest developments and the diversity of approaches and applications.
Pink shoes and a lab jacket: Finding your way as a female scientist
Women in science tell high school girls they, too, can change the world
PEOPLE IN YOUR NEIGHBORHOOD: Jazz piano in La Jolla scientist Clyde Hutchison’s DNA
How AI can help us decode immunity
Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
Construction of an Escherichia coli genome with fewer codons sets records
The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual — raising the prospect of encoding proteins that contain unnatural amino-acid residues.
Public Health is the Next Big Thing at UC San Diego
Researchers have swapped the genome of gut germ E. coli for an artificial one
By creating a new genome, scientists could create organisms tailored to produce desirable compounds
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