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Scientists Explore Genome of Methane-breathing Microbe
First Complete DNA Sequence of a Methanotroph Reveals Metabolic Flexibility, Suggests Mechanisms for Increasing Its Usefulness For Biotechnology
TIGR Scientists Explore Microbes on Shipwrecks and Coral
Researchers embarked on two separate expeditions this week to explore microbial communities on deep-sea corals in the Gulf of Alaska and on shipwrecks in the Gulf of Mexico.
Bioinformatics Resource Center at TIGR to Focus on Biothreat Pathogens
TIGR has signed a five-year, $21.1 million contract with the National Institute of Allergy and Infectious Diseases to establish and maintain a new national Bioinformatics Resource Center for the study of pathogens that are considered biothreat agents or are associated with emerging or re-emerging infectious diseases.
Anthrax Toxin Genes Found in Another Microbial Species
For the first time, researchers have found anthrax toxin genes in a naturally occurring microbe other than Bacillus anthracis, the bacterium that causes anthrax. The microbe that contains those anthrax genes is a strain of Bacillus cereus isolated from a patient with a medical condition similar to inhalation anthrax.
Decoding a Sulfate-Breathing Bug
Paving the way for better methods to protect pipelines and remediate metallic pollutants, TIGR scientists and collaborators have deciphered the genome of a sulfate-breathing bacterium, Desulfovibrio vulgaris, which can damage oil and natural gas pipelines and corrode oilfield equipment.
Scientists Decipher the Rat Genome
An international consortium of scientists that includes TIGR has completed a high-quality draft sequence of the rat genome. Comparing the rat to the human and mouse genomes, the Rat Genome Sequencing Project Consortium reported that nearly all human genes known to be associated with diseases have counterparts in the rat.
HP and TCAG Collaborate to Advance Medical and Environmental Genomic Discovery in Life Science
A New Spin on Spirochetes
Major Differences Found Between the Genomes of Oral Pathogen Treponema denticola and Related Spiral-Shaped Bacteria that Cause Syphilis and Lyme Disease
"Male-Targeting" Bacterium's Genome is Deciphered
Versatile Wolbachia has more mobile DNA than any other intracellular bacterium; Study may help in developing new treatments for diseases
IBEA Researchers Publish Results From Environmental Shotgun Sequencing of Sargasso Sea In Science; Discover 1,800 New Species And 1.2 Million New Genes, Including Nearly 800 New Photoreceptor Genes
IBEA Announces Sorcerer II Expedition, Global Expedition To Sample World's Oceans And Land To Characterize And Understand Microbial Populations Using Environmental DNA Sequencing
Gordon and Betty Moore Foundation give IBEA $4.25 Million Grant for Genomic Sequencing of DNA Samples from Expedition Discovery Channel to Film Expedition for TV Documentary
Discovery Channel to Film Expedition for TV Documentary
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Diatoms Have Found a Way to Pirate Bacterial Iron Sources
In large regions of the world’s oceans, photosynthesis struggles to operate because a key ingredient is missing. Many of the proteins involved in harvesting energy from sunlight require iron atoms to function, but iron is hard to find in seawater. Most of the ocean is far removed from...
The JCVI Genomic Frontier Fund
As we complete our 26th year as a private genomic research institution, we are still just as excited as we were in the very beginning to be making new discoveries, potentially ones that will change our society for the better. The knowledge gained from our study of DNA, or as Dr. Venter...
New Sequencing Technologies Enable Better and Faster Understanding of the Human Microbiome
Humans have trillions of different species of microorganisms living inside and on the human body. These microbes colonize on the skin, gut, oral cavity, vagina, internal organs, and circulating fluids, and are called the human microbiome. The human microbiome plays profound roles in health...
Human Microbiome Research has Massive Potential for Health Applications
Thirteen years ago, a team led by J. Craig Venter Institute President, Karen Nelson, Ph.D., published the first major human microbiome study, radically changing the way we look at human health and the role the microbes that inhabit each of us play in disease. This seminal publication...
Scientist Spotlight: Lauren Oldfield
Since high school, Lauren Oldfield, PhD found that science was her calling. It started with a love of reading encouraged by her mom and grandmother, both avid readers, and weekly trips to the public library. Books by Michael Crichton and Richard Preston were staples in her grandmother’s...
When Starved, Dangerous Oral Bacteria Hang On
J. Craig Venter Institute (JCVI) postdoctoral fellow, Jonathon Baker, PhD and a team of researchers from JCVI, University of Washington, the University of California, Los Angeles, and The Forsyth Institute recently published their findings from the first study to examine the ecological dynamics...
No More Needles! Using Microbiome and Synthetic Biology Advances to Better Treat Type 1 Diabetes
Learn about exciting advances made by JCVI researchers Yo Suzuki and John Glass who are on a quest to better understand and treat Type 1 Diabetes (T1D). Currently T1D is managed by injecting insulin to manage blood glucose levels. Drs. Suzuki and Glass want to change that by creating a...
How to Bake a (Fungal) Turkey
From the kitchen of Stephanie Mounaud, Scientific Project Manager at JCVI Ingredients Media base (see media recipe) Agar Aspergillus terreus (multiple strains) Aspergillus niger Aspergillus fumigatus Aspergillus oryzae...
Scientist Spotlight: Todd Michael
A love of science began for Todd Michael, PhD when his 7th grade teacher had him write a report on tree leaves. After collecting different leaves and looking up their tree type, he realized that although all of the trees were similar, they grew different types of leaves. He was certain there...
Fighting Back Against Flu
The 1918 influenza pandemic, which affected 500 million people globally and caused 50-100 million deaths, was the most severe pandemic in recorded history. Over the course of the last 100 years, advances in science and medicine have provided the tools to address influenza much more...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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