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Genome Analysis Sheds Light on Mobile DNA's Role in Pathogen's Resistance to Vancomycin
TIGR's sequencing and analysis of the genome of a vancomycin-resistant strain of Enterococcus faecalis has found that nearly a third of the genome consists of "mobile elements" -- segments of DNA that can jump between organisms or their chromosones -- that appear to play an important role in helping the bacterium quickly acquire resistance to drugs.
New Mobile Lab To Bolster Bioscience Education
The nation's newest and largest mobile laboratory, the MdBioLab, will be launched in early February to help Maryland high schools enhance their bioscience education programs. TIGR has partnered with MdBio, Inc., and the University of Maryland Biotechnology Institute to create this innovative non-profit project.
TIGR Offers Genomics Course
Rice Genome Sequence Announced By International Public Consortium
An international sequencing consortium that includes TIGR announced today that scientists have completed the assembly of an advanced, high-quality draft genome sequence of rice and made that data freely available. The sequence is an important new tool for agricultural and nutritional research involving one of the world's most important crops.
U.S.-German Research Consortium Sequences Genome of Versatile Soil Microbe
Pseudomonas putida Has Potential for Use in Bioremediation, Promoting Plant Growth and Fighting Plant Diseases
IBEA Receives $3 Million Dept. of Energy Grant for Synthetic Genome Development
Hamilton Smith, M.D., Nobel Laureate, Named Scientific Director of IBEA
Exploring Bacterial Branches of the Tree of Life
In an ambitious "phylogenomics" project, TIGR scientists have received an NSF grant to use whole genome sequence analysis to better understand the phylogenetic relationships among major bacterial groups.
Announcing the release of two packages useful in the analysis of shotgun sequence assembly data
TIGR evolutionary biologist Jonathan Eisen has been named as one of Esquire magazine's "Best and Brightest" innovators.
TIGR evolutionary biologist Jonathan Eisen has been named as one of Esquire magazine's "Best and Brightest" innovators. The list of 43 "emerging leaders who are reshaping our world" -- including nine scientists -- appears in the magazine's December issue.
TIGR Cracks Genome of Potential Bioremediation Agent
Scientists at TIGR and their collaborators have deciphered the genome sequence of the bacterium Shewanella oneidensis, which has great potential as a bioremediation agent to remove toxic metals such as chromium and uranium from the environment.
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10 Days of Italian Sampling Coming to a Close
Tuesday July 20th On July 16th we finished our Straits of Messina sampling and headed into the Ionian and Adriatic Seas. We sailed overnight and collected our Ionian Sea sample, we continued northeast and on July 18th we collected our Adriatic...
HMP Consortium - St. Louis Missouri
Human Microbiome Project Consortium – September 2010 – St Louis, Missouri We received warm welcome messages from Dr George Weinstock and Dr Jane Petersen as well as a humorous welcome from Dr Larry Shapiro, Dean of Washington University Medical School. It was wonderful to see so...
Straits of Messina Transect
Friday July 16th Today we woke up early and left our anchorage at Vulcano Island and headed to the Straits of Messina 20 miles away. The plan was to collect a sample at the north entrance, anchor for 5 hours to process the sample. Once the sample was completed then head to the middle of the...
Advance Access JCVI Metagenomics Reports Application Note
A significant JCVI informatics development is JCVI Metagenomics Reports, an open source Web 2.0 application designed to help scientists analyze and compare annotated metagenomics data sets. Users can download the application to upload and analyze their own metagenomics datasets. METAREP...
Naples Harbor Sampling
Thursday July 15th After getting some sleep at anchorage in Ischia island we sailed for a few hours to the main harbor in Naples. Over the years the Sorcerer II Expedition has collected samples in major ports around the world (Sydney, Halifax, Boston, Panama, Cape Town, just to...
Italian Sampling Continues-Unique Animal in Italian Waters!
Wednesday July 14th Monday July 12th we woke up early and left the anchorage in Capraia Island. We arrived at Ischia island at 5:00 a.m. on Wednesday the 14th. In those 48 hours we collected 6 samples. Two samples were collected in the Northern Tyrrhenian Sea, two samples were collected over...
Mediterranean Sampling Season Starts
Sunday July 11th 2010 On Thursday July 8th Sorcerer II set sail from Valencia Spain to start the Mediterranean season. Permits vary from country to country, Italy gave us 10 days to collect our samples, so we had to time our departure from Spain to fit our 10 day sampling window in Italy. As...
The Sorcerer II Sampling Process
July 6th In the blog about the media event I posted a few days back I put a link to the JCVI media page. On this page you can learn about our research goals, funders and past expeditions (more links on the right side of the page). Before we set out for this sampling season I wanted to...
Valencia, The Home Of Sorcerer II And Crew Since September 2009
July 5th Valencia is located about 140 miles (365 kilometers) from Barcelona. Valencia has a rich history and a distinct culture from other Spanish cities. I have only spent a few months here, but I wanted to share some of the highlights with you all before we set sail and start our...
High-performance comparative metagenomics
Are your carrying out large scale metagenomics analyses to identify differences among multiple sample sites? Are you looking for suitable analysis tools? If you have not yet found the right analysis tool, you may be interested in the latest beta version of JCVI...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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