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Scientists Decipher Genetic Code of Malaria Parasite
In a landmark contribution to the battle against malaria, scientists at TIGR and two other sequencing centers have deciphered the complex genetic code of the Plasmodium falciparum parasite that causes the deadliest form of the disease. In a related paper, a TIGR team also published a comparison of the genome with that of the model rodent malaria parasite, P. yoelii yoelii. And TIGR scientists played a role in sequencing the genome of the malaria-transmitting mosquito, Anophles gambiae.
Fraser Wins Lawrence Award
Secretary of Energy Spencer Abraham announced today that TIGR's president and director, Claire M. Fraser, Ph.D., will receive the E.O. Lawrence Award for her "contributions to genome analysis technology, its extension to the understanding of microbial diversity, and its application to human pathogens."
Towards the $1,000 Genome: "Hot Topic" Added to TIGR Genome Conference
Meeting Kicks Off With Keynote Lecture By Barry Bloom, Dean of Harvard's School of Public Health, Followed by Panel Discussion On New Sequencing Technologies
Genome of Potential Bioterror Agent Sequenced; Highlights Similarities Between Animal, Plant Pathogens
Scientists at TIGR, in collaboration with colleagues at three other research institutes, have determined the complete genomic sequence of Brucella suis, a bacterial pathogen and potential bioterrorism agent that could be targeted against humans or livestock.
Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
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10 Days of Italian Sampling Coming to a Close
Tuesday July 20th On July 16th we finished our Straits of Messina sampling and headed into the Ionian and Adriatic Seas. We sailed overnight and collected our Ionian Sea sample, we continued northeast and on July 18th we collected our Adriatic...
HMP Consortium - St. Louis Missouri
Human Microbiome Project Consortium – September 2010 – St Louis, Missouri We received warm welcome messages from Dr George Weinstock and Dr Jane Petersen as well as a humorous welcome from Dr Larry Shapiro, Dean of Washington University Medical School. It was wonderful to see so...
Straits of Messina Transect
Friday July 16th Today we woke up early and left our anchorage at Vulcano Island and headed to the Straits of Messina 20 miles away. The plan was to collect a sample at the north entrance, anchor for 5 hours to process the sample. Once the sample was completed then head to the middle of the...
Advance Access JCVI Metagenomics Reports Application Note
A significant JCVI informatics development is JCVI Metagenomics Reports, an open source Web 2.0 application designed to help scientists analyze and compare annotated metagenomics data sets. Users can download the application to upload and analyze their own metagenomics datasets. METAREP...
Naples Harbor Sampling
Thursday July 15th After getting some sleep at anchorage in Ischia island we sailed for a few hours to the main harbor in Naples. Over the years the Sorcerer II Expedition has collected samples in major ports around the world (Sydney, Halifax, Boston, Panama, Cape Town, just to...
Italian Sampling Continues-Unique Animal in Italian Waters!
Wednesday July 14th Monday July 12th we woke up early and left the anchorage in Capraia Island. We arrived at Ischia island at 5:00 a.m. on Wednesday the 14th. In those 48 hours we collected 6 samples. Two samples were collected in the Northern Tyrrhenian Sea, two samples were collected over...
Mediterranean Sampling Season Starts
Sunday July 11th 2010 On Thursday July 8th Sorcerer II set sail from Valencia Spain to start the Mediterranean season. Permits vary from country to country, Italy gave us 10 days to collect our samples, so we had to time our departure from Spain to fit our 10 day sampling window in Italy. As...
The Sorcerer II Sampling Process
July 6th In the blog about the media event I posted a few days back I put a link to the JCVI media page. On this page you can learn about our research goals, funders and past expeditions (more links on the right side of the page). Before we set out for this sampling season I wanted to...
Valencia, The Home Of Sorcerer II And Crew Since September 2009
July 5th Valencia is located about 140 miles (365 kilometers) from Barcelona. Valencia has a rich history and a distinct culture from other Spanish cities. I have only spent a few months here, but I wanted to share some of the highlights with you all before we set sail and start our...
High-performance comparative metagenomics
Are your carrying out large scale metagenomics analyses to identify differences among multiple sample sites? Are you looking for suitable analysis tools? If you have not yet found the right analysis tool, you may be interested in the latest beta version of JCVI...
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Craig Venter: 20 years of decoding the human genome
The human genome is 99% decoded, the American geneticist Craig Venter announced two decades ago. What has the deciphering brought us since then?
Scientists in La Jolla Make Progress Understanding New Coronavirus Strain
Gene Drives: New and Improved
As the science advances, policy-makers and regulators need to develop responses that reflect the latest developments and the diversity of approaches and applications.
Pink shoes and a lab jacket: Finding your way as a female scientist
Women in science tell high school girls they, too, can change the world
PEOPLE IN YOUR NEIGHBORHOOD: Jazz piano in La Jolla scientist Clyde Hutchison’s DNA
How AI can help us decode immunity
Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
Construction of an Escherichia coli genome with fewer codons sets records
The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual — raising the prospect of encoding proteins that contain unnatural amino-acid residues.
Public Health is the Next Big Thing at UC San Diego
Researchers have swapped the genome of gut germ E. coli for an artificial one
By creating a new genome, scientists could create organisms tailored to produce desirable compounds
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