Increased acidification shown to limit iron availability, a critical element for the survival of phytoplankton, the foundation of the oceanic food web
J. Craig Venter Institute scientists awarded five-year, $5.7M grant from NIH to develop phage treatment
Phage research accelerates with the rise of antibiotic resistance to address increasingly prevalent and difficult to treat bacterial infections
Bringing cells to life … and to Minecraft: $30 million NSF grant to support whole-cell modeling at the Beckman Institute
Beckman researchers and collaborators received $30 million from the U.S. National Science Foundation to establish the NSF Science and Technology Center for Quantitative Cell Biology. The center will develop whole-cell models to transform our understanding of how cells function and share that knowledge with diverse communities through the popular computer game Minecraft.
LJI researchers work to head off future pandemics by uncovering key similarities between SARS-CoV-2 and common cold coronaviruses
$8 million NIH grant supports effort to avert next pandemic
A $1 million grant from the Steven & Alexandra Cohen Foundation will launch a UC San Diego-led national effort to more deeply study tissue samples from patients with conditions ranging from long COVID-19 and relapsed Lyme disease to chronic fatigue syndrome
The Tissue Analysis Pipeline will be directed by scientists at UC San Diego and the J. Craig Venter Institute
JCVI recognizes trailblazers in scientific history, particularly those who made advancements all while surpassing gender, ethnic, and other societal barriers, creating opportunity for the next generation of scientists. These historical figures not only helped advance our understanding of human...
Tu Youyou is a Chinese pharmaceutical chemist whose unique training in the classification of medical plants and their active ingredients resulted in a discovery that has led to the survival and improved health of millions of people. In 1967, at the height of the Vietnam War, malaria spread by...
The Bacterial Viral Bioinformatic Resource Center (BV-BRC) is proud to introduce a new resource with the goal of providing live tracking of SARS-CoV-2 mutations. This real-time resource will provide regular reports focused on “Variants and Lineages of Concern” (VoCs/LoCs), and will serve as an early warning system for variants that are increasing in frequency in specific geographical locations.
JCVI Scientists and Interns Dramatically Trim Proteome Analysis Costs with New Lab-on-a-Filter Process
Through a happy accident and a keen mind, JCVI intern Rodrigo Eguez realized scientists might be able to pack their own filters rather than rely on those produced commercially at a significant cost savings. While playing around in the laboratory, he inadvertently disassembled a filter device...
Unique Antibody Pattern Discovered in COVID-19 ICU Patients May Be Key to Predicting Severe Outcomes
While news of promising COVID-19 vaccine trials is heartening, the fight to control infection rates and develop effective treatments will be an ongoing challenge for science for years to come. Gene Tan, PhD and his collaborators are working on identifying...
Early last year we first talked about how researchers Yo Suzuki, PhD, and John Glass, PhD at JCVI set out to eliminate the need for type 1 diabetes (T1D) patients to receive insulin injections to manage blood glucose levels through a novel approach: developing a bacterial replacement for beta...
While the world is rightly focused on the ongoing COVID-19 pandemic, it’s important to know that influenza is always a significant public health burden, and the combination of the pandemic and flu season could converge to become a perfect storm of infectious diseases. Influenza causes 3 to...
At the beginning of the 20th century, many people remained skeptical of both germ theory and preventative medicine, but pioneering physician Dr. Sara Josephine Baker fought to revolutionize public health and is credited with saving tens of thousands of lives. After studying chemistry and...
JCVI Researchers Help Advance Our Understanding of Ocean Microbes, Developing New Tools and Protocols Through Large-Scale Study
The oceans cover over two-thirds of the Earth’s surface and contain an abundance of life including diverse populations of marine microbes. Studying the genetics, biochemistry and metabolism of these microbes has been one of JCVI’s long standing research initiatives and is...
The COVID-19 pandemic has brought many changes to our daily lives and routines, including for many of you the role of an at-home educator for your children due to open-ended school closures. While we also miss directly connecting with students from our community, JCVI remains committed...
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
In a plenary public appearance at the Molecular and Precision Med TRI-CON event in San Diego, a relaxed Venter reflected on his career highlights, controversies and future priorities for genomic medicine.
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