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Scientists Decipher Genetic Code of Malaria Parasite
In a landmark contribution to the battle against malaria, scientists at TIGR and two other sequencing centers have deciphered the complex genetic code of the Plasmodium falciparum parasite that causes the deadliest form of the disease. In a related paper, a TIGR team also published a comparison of the genome with that of the model rodent malaria parasite, P. yoelii yoelii. And TIGR scientists played a role in sequencing the genome of the malaria-transmitting mosquito, Anophles gambiae.
Fraser Wins Lawrence Award
Secretary of Energy Spencer Abraham announced today that TIGR's president and director, Claire M. Fraser, Ph.D., will receive the E.O. Lawrence Award for her "contributions to genome analysis technology, its extension to the understanding of microbial diversity, and its application to human pathogens."
Towards the $1,000 Genome: "Hot Topic" Added to TIGR Genome Conference
Meeting Kicks Off With Keynote Lecture By Barry Bloom, Dean of Harvard's School of Public Health, Followed by Panel Discussion On New Sequencing Technologies
Genome of Potential Bioterror Agent Sequenced; Highlights Similarities Between Animal, Plant Pathogens
Scientists at TIGR, in collaboration with colleagues at three other research institutes, have determined the complete genomic sequence of Brucella suis, a bacterial pathogen and potential bioterrorism agent that could be targeted against humans or livestock.
Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
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Scientist Spotlight: Greg Wanger
Greg Wanger was 3.7 km below the Earth’s surface, trapped not only underground but also in a country distant from his native lands of Canada and Liechtenstein. He looked around him. It was very hot and smelled like rotten eggs. As many people do during their graduate careers, Greg pondered...
Digging out from the storm
The next day offered more snow and wind: we still needed handheld radios anytime we ventured between the warming hut and any of the vehicles. The wind was so strong that snow began drifting up through the dive hole in the warming hut, and the windows completely glazed over with snow. At one...
Out onto the ice
It took an enormous amount of effort, but on Thursday we ventured out onto the sea ice with our train of sleds and snow machines. The tucker is our strongest (and slowest) vehicle, and it is pulling both our yellow research sled and a pair of snowmobiles. The red Pisten-Bully is pulling a...
Around Mac-town
We are now fully packed and our mobile research sled is ready to go. We are waiting for some final repairs on the Pisten-Bully which will pull our supply sled. The mobile laboratory sled will be pulled by the Sno-Cat Tucker, which also has cab space for six (riding in the mobile lab would...
Ice diatoms!
Today has been a day of preparations, as tomorrow we hope to leave McMurdo Station and head out on the sea ice. Our mobile sled is almost ready for deployment: the carpenters who work for the US Antarctic Program are quite amazing, and our sled has filtration racks for separating different...
Sea-ice class
Today Abigail Noble and I took a Hagglund transporter out onto the Ross Sea to learn the basics of sea ice safety and ice dynamics. The sea ice on McMurdo Sound can be 2 meters thick, but this ice is constantly changing, and when you drive along its surface, you can't assume that it is...
Happy Camp
Our project on the Ross Sea will take us far from heated facilities of McMurdo Station, so all members of our team need to attend "Happy Camp", a two day course on snow camping and basic Antarctic survival. Happy Camp is held out on the McMurdo Ice Shelf, and it is an immersion program in...
McMurdo Station
Entering McMurdo is like entering a modern mining town: lots of exposed rock and unpaved streets, above ground utilities and bare-bones architecture. Utilitarian. From the airport we were taken to a briefing room, introduced to our science coordinators, and given our shcedules. Since I am...
Transport to the ice
Wednesday morning started with a 5AM taxi ride to the US Antarctic Program's processing center at the Christchurch airport, where we had to repack our bags and put on our emergency cold weather gear for the flight. Our plane was the C-17 Globemaster III, a large military transport plane more...
Polynya opens in the Ross Sea
A helicopter pilot recently sent us an image of the area we are planning to sample, and the stable sea ice we intended to use as a platform for drilling and sampling is now a giant stretch of open seawater! A large opening like this is a polynya, a term borrowed from the Russian...
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Craig Venter: 20 years of decoding the human genome
The human genome is 99% decoded, the American geneticist Craig Venter announced two decades ago. What has the deciphering brought us since then?
Scientists in La Jolla Make Progress Understanding New Coronavirus Strain
Gene Drives: New and Improved
As the science advances, policy-makers and regulators need to develop responses that reflect the latest developments and the diversity of approaches and applications.
Pink shoes and a lab jacket: Finding your way as a female scientist
Women in science tell high school girls they, too, can change the world
PEOPLE IN YOUR NEIGHBORHOOD: Jazz piano in La Jolla scientist Clyde Hutchison’s DNA
How AI can help us decode immunity
Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
Construction of an Escherichia coli genome with fewer codons sets records
The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual — raising the prospect of encoding proteins that contain unnatural amino-acid residues.
Public Health is the Next Big Thing at UC San Diego
Researchers have swapped the genome of gut germ E. coli for an artificial one
By creating a new genome, scientists could create organisms tailored to produce desirable compounds
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