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Scientists Decipher Genome of a Fungus That Causes Life-Threatening Infections in Persons With Impaired Immunity
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Scientists Reveal Molecular Secrets of the Malaria Parasite
Groundbreaking Research Project May Help Boost Vaccine Development
Scientists Decipher Genome of Bacterium that Helps Clean Up Major Groundwater Pollutants
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Genome Comparison of Four Campylobacter Strains Yields New Genetic Markers and Clues to Virulence
In a study that could benefit medical and food-safety research, scientists have used the tools of comparative genomics to find new clues about why some strains of the bacterium Campylobacter - which each year cause more than 400 million cases of gastrointestinal disease - are more virulent than others. The analysis is helping researchers develop more comprehensive detection methods for analyzing human and environmental isolates of the bacteria.
Microbe's Genome Reveals Insights Into Ocean Ecology
Unexpected findings about the genetic makeup of a marine microbe have given scientists a new perspective on how bacteria make a living in the ocean - a view that may prove useful in wider studies of marine ecology. The analysis by TIGR and collaborators of the DNA sequence of Silicibacter pomeroyi found that the metabolic strategies of marine bacterioplankton are more diverse and less conventional than previously thought.
Innovative Metagenomics Strategy Used To Study Oral Microbes
In an innovative new project, TIGR scientists and collaborators are using a metagenomics strategy to explore the complex mix of microbes in the human mouth. The research could help improve the diagnosis and treatment of periodontitis and other oral diseases.
Influenza Genome Sequencing Project Is Launched
TIGR will sequence a large number of human isolates of the influenza virus as part of a landmark influenza genome sequencing project announced Monday by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The project aims to help scientists better understand how flu viruses evolve as they spread through the population.
TIGR and Virginia Tech Sign Memorandum for New Alliance
A new alliance between TIGR and Virginia Tech University is expected to enhance the Institute's computational and experimental capacity as well as enrich the university's basic research in the life sciences. The Memorandum of Understanding, announced Monday, anticipates joint research projects, shared use of related facilities, adjunct faculty appointments, and opportunities for students to participate in research.
TIGR's Fraser, Salzberg Honored As AAAS Fellows
TIGR President Claire M. Fraser and Senior Bioinformatics Director Steven L. Salzberg have been named as Fellows of the American Association for the Advancement of Science (AAAS) in recognition of their contributions to genomics and bioinformatics.
Computational Genomics Conference To Attract Leading Scientists
Comparative genomics, sequence assembly, gene expression analysis and genome annotation are among the hot topics to be discussed at the 7th annual Conference on Computational Genomics, which will be held October 21-24 in Reston, VA. The meeting is jointly sponsored by TIGR and The Jackson Laboratory.
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Media Day Circus On Sorcerer II
June 23nd On Monday June 21st we announced the official start of the Mediterranean leg of the Sorcerer II Global Ocean Sampling Expedition. Dr. Venter took time from his busy schedule to fly into Valencia and attend the event as well as representatives from The Life Technology Foundation....
Genomics of the Indoor Air Environment
Most of our life is spent in indoors, well-buffered from the constant changes in temperature, humidity, wind and light which shape life outside our homes and offices. It seems intuitive that the types of microorganisms which inhabit our indoor environment must be different from those on the...
Sorcerer II back at Sea!
June 13th 2010 After we collected and processed the sample from Blanes on May 26th we dropped off the collaborators on the dock, and set sail for France. After a overnight sail we reached our last Spanish sample site, it is in Spanish waters but monitored by French scientist. CTD...
The Re-Sampling of Blanes By Karolina Ininbergs
May 26th 2010 After docking in Barcelona and picking up Jeff, who just finished the lake sampling with Chris up in the Pyrenees, we headed north-east towards Blanes Bay. We were also joined by Bea Diez, her PhD student Roy McKenzie, Meri Antó and Vanessa Balague from ICM, Barcelona. It was...
BBMO — Blanes Bay Microbial Observatory
May 25th 2010 In 2008 I spent three months working at the Institute of Marine Sciences in Barcelona, hosted by Beatriz Diez in the Marine Microbiology group, headed by Carles Pedrós-Alió. One of the many microbial research projects at ICM is focused on environmental monitoring of...
Tourist Time in Barcelona!
May 20th 2010 After two weeks on the road, I am back on Sorcerer II as we prepare for the Mediterranean sampling season. We are docked in Port Olympic right in the heart of Barcelona. One aspect of this year's blogs is to share some of the experiences and places we get to visit. We are...
The Great Blizzard Sample of Lake Redon!
May15th 2010 We decided to do the 3 lakes in the Banyoles area first because the weather in the Pyrenees was so bad that we wouldn't have been able to get up the mountain to sample Lake Redon. Lake Redon is a pristine Alpine lake that is sampled weekly by Spanish researchers. On Tuesday May...
Lake Vilar, The Final Lake In Banyoles
May 10th 2010 On Monday May 10th we headed back to sample the last lake in the Banyoles area. Lake Vilar is another meromictic lake located about 1 kilometer (1/2 mile) from Lake Siso and has a maximum depth of 10 meters (32 feet). Sulfide is present during the entire year, although...
Sampling of Lake Banyoles, The Home of the Olympic Rowing in 1992
May 9th 2010 Sunday May 9th was a much better morning than the previous one. Emilio had taken us out to one of the best dinners I have ever eaten, plus the German teenagers were no longer patrolling the hallways all night long. So after a great seafood dinner and a good nights rest we drove...
Lake Sampling Starts with Lake Siso, Global Lake Sampling (GLS)
May 8th 2010 Early on Saturday May 8th Chris and I headed to the University of Girona, which is located about 69 kilometers (42 miles) from Blanes, to setup our sampling gear in a aboratory on campus. We were a bit exhausted from the long drive the day before and lack of sleep due to lots of...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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