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Artificial cells demonstrate that “life finds a way”
Family resemblance: How T cells could fight many coronaviruses at once
LJI researchers work to head off future pandemics by uncovering key similarities between SARS-CoV-2 and common cold coronaviruses
Scientists aim to develop vaccine against all deadly coronaviruses
$8 million NIH grant supports effort to avert next pandemic
What are the Drivers of Chronic Infectious Disease?
A $1 million grant from the Steven & Alexandra Cohen Foundation will launch a UC San Diego-led national effort to more deeply study tissue samples from patients with conditions ranging from long COVID-19 and relapsed Lyme disease to chronic fatigue syndrome
The Tissue Analysis Pipeline will be directed by scientists at UC San Diego and the J. Craig Venter Institute
BullFrog AI Partners with J. Craig Venter Institute to Develop Colorectal Cancer Therapeutic
Collaboration seeks to develop an oncolytic virus that incorporates a novel, precision-targeted approach to improve safety and efficacy
JCVI Associate Professor Marcelo Freire elected to the 2022 class of AAAS Fellows
More Than 500 Scientists and Engineers Bestowed Lifetime AAAS Fellows Honor
Therapeutic Potential of Bizarre ‘Jumbo’ Viruses Tapped for $10M HHMI Emerging Pathogens Project
UC San Diego leads initiative aiming to develop bacteriophages as solutions for antibiotic resistance crisis
HHMI’s Emerging Pathogens Initiative Aims for Scientific Head Start on Future Epidemics
Synthetic genomics advances and promise
Advances in DNA synthesis will enable extraordinary new opportunities in medicine, industry, agriculture, and research
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The Hill School: Day 1
The day started early with reagent and lab preparation before we even left for school OR had coffee. We expected to do over 100 DNA Extractions as the first step in the DNA Barcoding. We arrived on campus as the first period was starting –we didn’t have class until after 9:00....
The Mobile Laboratory Hits the Road
After a hiatus this summer, the Mobile Laboratory hit the road again today for a trip to Pottstown, Pennsylvania. Driving through the rolling hills of northern Maryland into southeastern Pennsylvania, it passed small towns and beautiful foliage. Tomorrow and Tuesday, we will be...
Sequencing of high yield influenza reassortants at JCVI
As part of the Influenza Genome Sequencing Project, JCVI will be sequencing a large number of high yield influenza reassortants created in the lab of Dr. Doris Bucher at New York Medical College. Dr. Bucher’s lab has prepared the type A H3N2 high yield reassortants (hyrs) for the...
What Happened to Sorcerer II?!?!
The last time I wrote a Sorcerer II blog was in November when we set sail from Spain to cross the Atlantic Ocean. For all of you that have been worried that we have been at sea for 8 months, relax we made it!! Over the next few days I will update everyone on what has happened and the upcoming...
Podcast on Human Genomics
The 2011 Festival of Ideas themed, The Pursuit of Identity, Landscape, History, and Genetics, is held every other year in Melbourne, Australia to inspire scholars and citizens alike in topics ranging from literature and art to science and foreign policy. JCVI Professor of Genomic...
Summit on Systems Biology, June 15-17, 2011
I attended the Summit on Systems Biology hosted by Virginia Commonwealth University in Richmond, VA June 15-17. So, judging from the talks given, what is systems biology? Systems biology is non-linear and/or multi-step. Heavy math does not make something systems biology if...
Insights gained from influenza genomic sequence data: viral diversity within human populations
The advent of large amounts of influenza genomic sequence data produced by the Influenza Genome Sequencing Project (IGSP) has led to new concepts regarding influenza viral diversity. It was previously believed that a single influenza lineage entered a human population at the start of an...
NASA and JCVI host symposium on the evolution of Earth and Life
On May 12th and 13th, the J. Craig Venter Institute in San Diego will be hosting a NASA Astrobiology Institute-funded symposium titled “Paleobiology in the genomics era.” Paleobiology is the study of the origins and evolution of life and, by nature, is interdisciplinary. The goal is to...
JCVI Supports Human Mircrobiome Body Site Experts with Shotgun Data Analysis
Members of the Human Microbiome Project (HMP) Consortium (see http://commonfund.nih.gov/hmp and http://www.hmpdacc.org for more information on the project and partners) including human microbiome body site experts gathered for a virtual Jamboree January 19th. The fully online-based Jamboree...
The Microbiome of Esophageal Cancer
In anticipation of the International Human Microbiome Congress, our group has diligently worked to generate data to present for our HMP demo project studying the microbiome of patients who have developed esophageal cancer, gastrointestinal reflux disease, and barrett’s esophagus. We...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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