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Scientists Decipher Genetic Code of Malaria Parasite
In a landmark contribution to the battle against malaria, scientists at TIGR and two other sequencing centers have deciphered the complex genetic code of the Plasmodium falciparum parasite that causes the deadliest form of the disease. In a related paper, a TIGR team also published a comparison of the genome with that of the model rodent malaria parasite, P. yoelii yoelii. And TIGR scientists played a role in sequencing the genome of the malaria-transmitting mosquito, Anophles gambiae.
Fraser Wins Lawrence Award
Secretary of Energy Spencer Abraham announced today that TIGR's president and director, Claire M. Fraser, Ph.D., will receive the E.O. Lawrence Award for her "contributions to genome analysis technology, its extension to the understanding of microbial diversity, and its application to human pathogens."
Towards the $1,000 Genome: "Hot Topic" Added to TIGR Genome Conference
Meeting Kicks Off With Keynote Lecture By Barry Bloom, Dean of Harvard's School of Public Health, Followed by Panel Discussion On New Sequencing Technologies
Genome of Potential Bioterror Agent Sequenced; Highlights Similarities Between Animal, Plant Pathogens
Scientists at TIGR, in collaboration with colleagues at three other research institutes, have determined the complete genomic sequence of Brucella suis, a bacterial pathogen and potential bioterrorism agent that could be targeted against humans or livestock.
Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
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The Mobile Laboratory Hits the Road
After a hiatus this summer, the Mobile Laboratory hit the road again today for a trip to Pottstown, Pennsylvania. Driving through the rolling hills of northern Maryland into southeastern Pennsylvania, it passed small towns and beautiful foliage. Tomorrow and Tuesday, we will be...
Sequencing of high yield influenza reassortants at JCVI
As part of the Influenza Genome Sequencing Project, JCVI will be sequencing a large number of high yield influenza reassortants created in the lab of Dr. Doris Bucher at New York Medical College. Dr. Bucher’s lab has prepared the type A H3N2 high yield reassortants (hyrs) for the...
What Happened to Sorcerer II?!?!
The last time I wrote a Sorcerer II blog was in November when we set sail from Spain to cross the Atlantic Ocean. For all of you that have been worried that we have been at sea for 8 months, relax we made it!! Over the next few days I will update everyone on what has happened and the upcoming...
Podcast on Human Genomics
The 2011 Festival of Ideas themed, The Pursuit of Identity, Landscape, History, and Genetics, is held every other year in Melbourne, Australia to inspire scholars and citizens alike in topics ranging from literature and art to science and foreign policy. JCVI Professor of Genomic...
Summit on Systems Biology, June 15-17, 2011
I attended the Summit on Systems Biology hosted by Virginia Commonwealth University in Richmond, VA June 15-17. So, judging from the talks given, what is systems biology? Systems biology is non-linear and/or multi-step. Heavy math does not make something systems biology if...
Insights gained from influenza genomic sequence data: viral diversity within human populations
The advent of large amounts of influenza genomic sequence data produced by the Influenza Genome Sequencing Project (IGSP) has led to new concepts regarding influenza viral diversity. It was previously believed that a single influenza lineage entered a human population at the start of an...
NASA and JCVI host symposium on the evolution of Earth and Life
On May 12th and 13th, the J. Craig Venter Institute in San Diego will be hosting a NASA Astrobiology Institute-funded symposium titled “Paleobiology in the genomics era.” Paleobiology is the study of the origins and evolution of life and, by nature, is interdisciplinary. The goal is to...
JCVI Supports Human Mircrobiome Body Site Experts with Shotgun Data Analysis
Members of the Human Microbiome Project (HMP) Consortium (see http://commonfund.nih.gov/hmp and http://www.hmpdacc.org for more information on the project and partners) including human microbiome body site experts gathered for a virtual Jamboree January 19th. The fully online-based Jamboree...
The Microbiome of Esophageal Cancer
In anticipation of the International Human Microbiome Congress, our group has diligently worked to generate data to present for our HMP demo project studying the microbiome of patients who have developed esophageal cancer, gastrointestinal reflux disease, and barrett’s esophagus. We...
A Look Back at 2010 at the JCVI…
As the J. Craig Venter Institute (JCVI) soars into its 19th year, we reflect on the past year of highlights and accomplishments to mark the close 2010 and look forward to more significant scientific advances in 2011. JCVI Top 10 of 2010 ... 1. First Synthetic Cell: Fifteen years in the...
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Sailing the Seas in Search of Microbes
Projects aimed at collecting big data about the ocean’s tiniest life forms continue to expand our view of the seas.
What the Public Should Not Know
J. Craig Venter, PhD, argues scientists have “a moral obligation to communicate what they're doing to the public,” and that more studies deserve greater public criticism.
Scientists coax cells with the world’s smallest genomes to reproduce normally
The discovery could sharpen scientists’ understanding of which functions are crucial for normal cells and what the many mysterious genes in these organisms are doing
San Diego arts, health, science and youth groups to share $71M from Prebys Foundation
The J. Craig Venter Institute is the recipient of three awards totaling more than $1.5M to study SARS-CoV-2 and heart disease
Reflections on the 20th Anniversary of the First Publication of the Human Genome
A new wave of research is needed to make ample use of humanity’s “most wondrous map”
Scientists rush to determine if mutant strain of coronavirus will deepen pandemic
U.S. researchers have been slow to perform the genetic sequencing that will help clarify the situation
After saving countless lives, Nobel laureate Hamilton Smith retires as his own health falters
He has been a fixture in San Diego science for decades
The 'Wondrous Map': Charting of the Human Genome, 20 Years Later
Twenty years ago, President Bill Clinton announced completion of what was arguably one of the greatest advances of the modern era: the first draft sequence of the human genome.
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