Publications

Journal of bacteriology. 2006-11-01; 188.21: 7700-6.

Novel conserved assembly factor of the bacterial flagellum

Titz B, Rajagopala SV, Ester C, Häuser R, Uetz P

PMID: 16936039

Abstract

TP0658 (FliW) and its orthologs, conserved proteins of unknown function in Treponema pallidum and other species, interact with a C-terminal region of flagellin (FlaB1-3 in T. pallidum; FliC in most other species). Mutants of orthologs in Bacillus subtilis and Campylobacter jejuni (yviF, CJ1075) showed strongly reduced motility. TP0658 stabilizes flagellin in a way similar to FliS, suggesting that TP0658 is a conserved assembly factor for the bacterial flagellum.

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