Publications

Molecular vision. 2007-03-26; 13.431-42.

Cloning and characterization of canine PAX6 and evaluation as a candidate gene in a canine model of aniridia

Hunter LS, Sidjanin DJ, Hijar MV, Johnson JL, Kirkness E, Acland GM, Aguirre GD

PMID: 17417604

Abstract

Mutations in PAX6 cause human aniridia. The small eye (sey) mouse represents an animal model for aniridia. However, no large animal model currently exists. We cloned and characterized canine PAX6, and evaluated PAX6 for causal associations with inherited aniridia in dogs.

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