Sinem Beyhan is an associate professor working in the Infectious Disease group. She is also an adjunct professor at UC San Diego and San Diego State University.
Dr. Beyhan’s research focuses on microbe-host interactions. She is particularly interested in the discovery of anti-fungal molecules, elucidation of gene pathways in Burkholderia and discovery of anti-Burkholderia drugs, and fungal genome assembly and annotation. Prior to her appointment at JCVI, Dr. Beyhan was a post-doctoral fellow at the University of California, San Francisco, where she was awarded American Lung Association Senior Research Training Fellowship, American Cancer Society Postdoctoral Fellowship and NIH-NIAID Pathway to Independence Award (K99/R00).
She received her PhD in Microbiology and Environmental Toxicology from the University of California, Santa Cruz, and her BS in Molecular Biology and Genetics from the Middle East Technical University, Ankara, Turkey.
Mapping genetic networks that control cell morphology and virulence in the fungal pathogen Histoplasma capsulatum
- Identification and characterization of regulatory factors that control the parasitic yeast form of H. capsulatum
- Identification and characterization of sensory proteins that are important for sensing and responding to host signals
- Identification and characterization of H. capsulatum virulence factors
Characterization of the factors that contribute to environmental and intracellular survival of the bacterial pathogen Burkholderia pseudomallei
- Determining the molecular mechanism of biofilm formation in B. pseudomallei
- Development of novel combination drug therapies to combat persistent B. pseudomallei infections
Characterization of the interactions between human gut microbiota and gut epithelial cells
- Characterization of secreted factors of Bacteroides species for their roles in interacting with human gut epithelial cells