
Related
Nacyra Assad-Garcia is a Staff Scientist who joined the JCVI in 2002 from Celera. For the past 15 years she has been a microbiologist specializing in Mycoplasma genomics. She is an integral member of the synthetic biology team with expertise in manipulating and transplanting mycoplasma genomes (up to 1.1 Mb). This technology enables the changing of one mycoplasma species into another and is essential for the creation of synthetic and minimized cells. These techniques will be useful to understand basic cellular processes. She will drive the wet lab work on a new project attempting to create the first vaccine for Africa Swine Fever Virus, the virus that causes porcine hemorrhagic fever primarily affecting pig-holders in Africa.
Nacyra received her BSc degree from the National Autonomous University of Nuevo Leon, Monterrey, Mexico. After graduating, Nacyra worked for CINVESTAV-IPN Unidad Irapuato in Irapuato, Mexico. She was then recruited to Life Technologies, Gaithersburg, MD and subsequently to Celera, Rockville, MD.
Awards
- Dexter Patent Award: "Regeneration of Plants using a new plant hormone". Life Technologies, Inc. AgBiotech Group. 1999.
- Monthly Recognition Award for "Continued Achievement". CINVESTAV-IPN, Inc.1994.
Granted Patents
Installation of genomes or partial genomes into cells or cell-like systems
Patent number: 9434974
Abstract: A method is provided for introducing a genome into a cell or cell-like system. The introduced genome may occur in nature, be manmade with or without automation, or may be a hybrid of naturally occurring and manmade materials. The genome is obtained outside of a cell with minimal damage. Materials such as a protein, RNAs, polycations, nucleoid condensation proteins, or gene translation systems may accompany the genome. The genome is installed into a naturally occurring cell or into a manmade cell-like system. A cell-like system or synthetic cell resulting from the practice of the provided method may be designed and used to yield gene-expression products, such as desired proteins. By enabling the synthesis of cells or cell-like systems comprising a wide variety of genomes, accompanying materials and membrane types, the provided method makes possible a broader field of experimentation and bioengineering than has been available using prior art methods.
Type: Grant
Filed: December 22, 2006
Date of Patent: September 6, 2016
Assignee: Synthetic Genomics, Inc.
Inventors: John I. Glass, Lei Young, Carole Lartigue, Nacyra Assad-Garcia, Hamilton O. Smith, Clyde A. Hutchison, J. Craig Venter
Auxinic analogues of indole-3-acetic acid
Patent number: 6815205
Abstract: The present invention provides compounds and compositions capable of stimulating plant growth, regeneration of plant cells and tissues, and transformation of plant cells and tissues, comprising mono- and multi-substituted auxinic analogues of indole-3-acetic acid (IAA) comprising substituent groups such as halo-, alkyl-, alkoxy-, acyl-, acylamido- and acyloxy-groups. The invention relates to a method of using such mono- and multi-substituted auxinic analogues of IAA to affect growth, regeneration or transformation in monocotyledonous and dicotyledonous plants, as well as in transgenic plant tissues. The invention also contemplates the use of these auxinic IAA analogues in the presence of other plant growth regulators, such as cytokinin, etc., to enhance plant growth.
Type: Grant
Filed: February 6, 2001
Date of Patent: November 9, 2004
Assignee: Invitrogen Corporation
Inventors: Jhy-Jhu Lin, Jianqing Lan, Nacyra Assad-Garcia
Regeneration of both plant tissues and transgenic plant tissues using a new plant hormone, 5-bromoindole-3-acetic acid
Patent number: 6610544
Abstract: The present invention describes the use of 5-bromoindole-3-acetic acid (5-B-IAA) as an auxin affecting plant cell growth. The invention relates to the use of 5-B-IAA compositions to affect growth in monocotyledonous as well as in dicotyledonous plants. The invention also describes the use of 5-B-IAA in plant growth affecting compositions for the regeneration of both plant tissues and transgenic plant tissues. Further, the invention provides plant growth affecting compositions comprising 5-B-IAA alone or in a mixture comprising one or more additional plant growth regulators, such as cytokinin, etc.
Type: Grant
Filed: August 7, 2001
Date of Patent: August 26, 2003
Assignee: Invitrogen Corp National
Inventors: Jhy-Jhu Lin, Jianqing Lan, Nacyra Assad-Garcia
Regeneration of both plant tissues and transgenic plant tissues using a new plant hormone, 5-bromoindole-3-acetic acid
Patent number: 5994135
Abstract: The present invention describes the use of 5-bromoindole-3-acetic acid (5-B-IAA) as an auxin affecting plant cell growth. The invention relates to the use of 5-B-IAA compositions to affect growth in monocotyledonous as well as in dicotyledonous plants. The invention also describes the use of 5-B-IAA in plant growth affecting compositions for the regeneration of both plant tissues and transgenic plant tissues. Further, the invention provides plant growth affecting compositions comprising 5-B-IAA alone or in a mixture comprising one or more additional plant growth regulators, such as cytokinin, etc.
Type: Grant
Filed: May 22, 1997
Date of Patent: November 30, 1999
Assignee: Life Technologies, Inc.
Inventors: Jhy-Jhu Lin, Jianqing Lan, Nacyra Assad-Garcia
Research Priorities
- Make available methods and technics developed for Mycoplasmas and publications.
- Establishing new technologies for Africa Swine Fever.
Publications
Research Priorities
- Make available methods and technics developed for Mycoplasmas and publications.
- Establishing new technologies for Africa Swine Fever.
Viral Synthetic Genomics to Engineer Large dsDNA Viruses
Rapid engineering of large dsDNA viruses using synthetic genomics assembly tools.