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Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
TIGR's informatics group today posted the third major release (3.0) of the genome annotation for the model plant Arabidopsis thaliana
TIGR investigators announced today that they have determined the complete genome sequence of a green-sulfur bacterium, Chlorobium tepidum
TIGR's new publication, the TIGR Triptych, features articles about Bacillus anthracis research and the new Pathogen Functional Genomics Resource Center
An Arabidopsis whole genome chip jointly developed by TIGR and Affymetrix Inc. has been completed and is now being tested
Scientists Find New Markers For Anthrax Isolates
In a pioneering use of genomics as a tool for the forensic analysis of microbes, TIGR scientists have found new genetic markers to distinguish the Bacillus anthracis isolate that was used in last fall's bioterror attack in Florida from closely related anthrax strains.
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Back on The Road, Mar Menor to Blanes, Spain
May 7th 2010 After a successful day of sampling in Mar Menor and a great local dinner of lobster paella, Chris and I loaded up the van and got back on the road early Friday morning. We had a 757 kilometer (470 miles) drive ahead of us to arrive in Blanes to meet with a team of collaborators...
The Green Lagoon — Sampling in Albufera de Valencia
During our sampling in Spain last year Chris and I met up with Francisco Rodriguez-Valera. Francisco had some great suggestions for sampling sites and one of them was Albufera de Valencia, a shallow hypertrophic fresh water lagoon, located just 30 minutes drive south of Valencia . When...
Road Sampling Starts in Mar Menor, Spain
Before sampling was to resume on Sorcerer II, a 2 week multiple-site road sampling trip was planned. Chris Dupont arrived in Valencia a day after me, in the next two days we would load up a giant rental van and hit the road. On Wednesday May 5th we drove the 322 kilometers (200 miles) from...
Return to Sorcerer II, The Mediterranean Season
Hello everyone! On May 2nd I flew from San Diego to rejoin Sorcerer II in Valencia Spain. Sorcerer II has been in Spain since our last sample in November, during that time her crew has been very busy upgrading systems and getting the rig certified. Sorcerer II is looking great and is ready for...
Looking for a Few Good Genomes (to sequence)!
The JCVI is one of three centers funded by the National Institutes of Allergy and Infectious Disease (NIAID) to provide sequencing and genotyping services to the infectious disease community. We are continually looking for researchers who would like to have organisms of research interest to...
Influences of trace metals on biological evolution
Scientists show how trace metal chemistry and global changes in oxygen have influenced the evolution of metalloproteins and the Eukaryotes A paper is being published in PNAS this week about how the varying abundance of trace metals in the environment has influenced biological...
JCVI Scientists Recognized by ASM
Drs. Karen E. Nelson and Kenneth H. Nealson are both being recognized by the American Academy of Microbiology (ASM) tomorrow, May 26, 2010. Karen has been elected to Fellowship in the ASM. She is one of seventy-eight new members that have been selected through a peer-review process based on...
Scientist Spotlight: Hamilton O. Smith and Clyde A. Hutchison III
Two of the superstars of science at the helm of the effort to make a synthetic cell (a cell with a completely man-made set of genetic instructions) are Hamilton Smith and Clyde Hutchison, or Ham and Clyde as they are affectionately known to colleagues. Since 2003 when they started working...
Happy DNA Day!
This past March, we had a great time participating in the science programs in San Diego. We ended the month with the SD Science Festival with over 30,000 participants. It was such a busy day - I forgot to take pictures. The venue was Petco Park with hundreds of exhibits and hands-on...
Recomb - Computational Proteomics
I recently attended the Recomb satellite conference on Computational Proteomics (downloads for talk and poster) in San Diego, CA. It was a kind of homecoming for me. I was a computational proteomics researcher at UCSD as a grad student with Vineet Bafna. Many of my classmates were still there,...
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Scientists rush to determine if mutant strain of coronavirus will deepen pandemic
U.S. researchers have been slow to perform the genetic sequencing that will help clarify the situation
After saving countless lives, Nobel laureate Hamilton Smith retires as his own health falters
He has been a fixture in San Diego science for decades
The 'Wondrous Map': Charting of the Human Genome, 20 Years Later
Twenty years ago, President Bill Clinton announced completion of what was arguably one of the greatest advances of the modern era: the first draft sequence of the human genome.
Craig Venter: 20 years of decoding the human genome
The human genome is 99% decoded, the American geneticist Craig Venter announced two decades ago. What has the deciphering brought us since then?
Scientists in La Jolla Make Progress Understanding New Coronavirus Strain
Gene Drives: New and Improved
As the science advances, policy-makers and regulators need to develop responses that reflect the latest developments and the diversity of approaches and applications.
Pink shoes and a lab jacket: Finding your way as a female scientist
Women in science tell high school girls they, too, can change the world
PEOPLE IN YOUR NEIGHBORHOOD: Jazz piano in La Jolla scientist Clyde Hutchison’s DNA
How AI can help us decode immunity
Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
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