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Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
TIGR's informatics group today posted the third major release (3.0) of the genome annotation for the model plant Arabidopsis thaliana
TIGR investigators announced today that they have determined the complete genome sequence of a green-sulfur bacterium, Chlorobium tepidum
TIGR's new publication, the TIGR Triptych, features articles about Bacillus anthracis research and the new Pathogen Functional Genomics Resource Center
An Arabidopsis whole genome chip jointly developed by TIGR and Affymetrix Inc. has been completed and is now being tested
Scientists Find New Markers For Anthrax Isolates
In a pioneering use of genomics as a tool for the forensic analysis of microbes, TIGR scientists have found new genetic markers to distinguish the Bacillus anthracis isolate that was used in last fall's bioterror attack in Florida from closely related anthrax strains.
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Polynya opens in the Ross Sea
A helicopter pilot recently sent us an image of the area we are planning to sample, and the stable sea ice we intended to use as a platform for drilling and sampling is now a giant stretch of open seawater! A large opening like this is a polynya, a term borrowed from the Russian...
Christchurch, New Zealand
Greetings from Christchurch, New Zealand, the anteroom to Antarctica. My colleagues and I have been here for several days now, running last minute errands, getting equipped with cold weather gear, and waiting for a flight south to McMurdo Station. The flight here was remarkable only in it's...
Why Antarctica, and why now?
So why are you going to Antarctica, and why are you going now? A very logical question... basically we are traveling to Antarctica to study microscopic marine plants known as phytoplankton. These organisms range in size from bacteria to diatoms to colonial algae, but all phytoplankton have two...
Trip preparations (inaugural posting!)
Well, we have less than a week left, and we are finalizing and shipping the chemicals and equipment we will need for sampling below the sea ice in the Ross Sea. We have already shipped out several hundred pounds of gear, and more await us in storage down at McMurdo Station in Antarctica....
Going west!
After saying good bye to our new friends in Rostock/Warnemünde I was looking forward to coming back to Swedish waters, this time a bit saltier, on the west coast. There are two marine field stations on the Swedish west coast belonging to The Sven Lovén Center for Marine Sciences. Our first...
In the bloom...almost
Cyanobacterial blooms during the summer are reoccurring phenomena in the Baltic Sea. This summer we have already encountered the two main species responsible the blooms, Aphanizomenon sp. and the toxin producing Nodularia spumigena (see previous posts), but so far not in the abundance that...
In the Deep
After the brief stop in my hometown we continue our journey southward in the Baltic proper. Our first sampling site was the Landsort deep, the very deepest part of the Baltic Sea (459 meters!) and a long-term monitoring and sampling site for various Swedish and international scientists...
The Midnight Sun and Fermented Fish
We returned from Abisko on Thursday July 9th around 10 p.m. The next morning was very busy for the crew as we had to put the science gear back together, prepare the boat, and do local newspaper and radio interviews. Read the interview: paper Like the transect north, our...
ROAD TRIP! Watch Out Arctic Circle...the Sorcerer II Sampling Team is Coming Your Way!
After we arrived in Luleå, Jeremy, Karolina and I started packing for our road sampling trip to Lake Torneträsk, a freshwater lake located in the Arctic Circle. Dr. Erling Norrby had contacted Dr. Christer Jonasson, the deputy director of the Abisko Scientific Research Station, to help...
Sunset at Norrbyskär
It was another beautiful morning in the Gulf of Bothnia as we left Härnösand. We stopped at another sampling site before meeting with a boat from Umeå Marine Research Station (UMF). We were greeted by UMF scientist Dr. Johan Wikner and a television crew. We docked at Norrbyskär, a...
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J. Craig Venter Describes a Human Genomics Revolution Still In Progress
Despite profound impact on bio-medical research, progress in understanding has been slow
Scientist renowned for study of adolescent brains named president of J. Craig Venter Institute
Anders Dale says he will move roughly $10 million in NIH funding from UCSD to JCVI.
Mirror Bacteria Research Poses Significant Risks, Dozens of Scientists Warn
Synthetic biologists make artificial cells, but one particular kind isn’t worth the risk.
Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
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