Entamoeba Vesicular Trafficking (section 6)
A number of vesicular trafficking molecules have been characterized in the
Entamoeba histolytica genome including the coatomer proteins (COP) COPI,
COPII, clathrin-coated vesicles, ADP-ribosylation factor (Arf) proteins,
secretion-associated Ras-related (Sar) proteins, Adapter Proteins (APs) and soluble
N-ethylmaleimide-sensitive factor attachment protein receptors (SNARE)
and will be available as supplementary tables to the
Advances
in Parasitology Review entitled "Structure and Content of the Entamoeba histolytica
Genome" (submitted).
Vesicular trafficking genes are presented in the supplementary table: The total number of putative genes encoding representative proteins involved in
vesicular trafficking in Entamoeba histolytica. The number of putative
genes for Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster,
Homo sapiens and Arabidopsis thaliana and the corresponding references are
presented. Links to the corresponding PubMed IDs for the References are
listed, below.
Footnote:
Entamoeba histolytica Gene name 10 (b+c): note that the value of
10 corresponds to both the Qb and Qc genes.
References:
(1)
Bock et al. 2001;
(2) Wennerberg
et al. 2005;
(3) Pasqualato et
al. 2002;
(4) Pereira-leal
et al. 2001;
(5) Burri
et al. 2004;
(6) Uemura
et al. 2004;
(7) Sanderfoot
et al. 2000;
(8) Boehm et al. 2001.
| Gene Name
| Entamoeba histolytica |
Saccharomyces cerevisiae |
Caenorhabditis elegans |
Drosophila melanogaster |
Homo sapiens |
Arabidopsis thaliana |
References |
| Sar1 |
1 |
1 |
1 |
1 |
2 |
4 |
1,2
|
| COPII |
9 |
6 |
5 |
4 |
9 |
12 |
1
|
| Arf |
10 |
6 |
11 |
11 |
25 |
17 |
3
|
| COPI |
11 |
7 |
7 |
7 |
9 |
9 |
1
|
| AP-1 |
|
5 |
7 |
5 |
8 |
9 |
|
| AP-2 |
|
4 |
5 |
5 |
5 |
6 |
|
| AP-3 |
|
4 |
4 |
4 |
7 |
4 |
|
| AP-4 |
|
0 |
0 |
0 |
4 |
4 |
|
| AP total |
18 |
13 |
16 |
14 |
24 |
23 |
1
|
| Rab |
91 |
11 |
29 |
26 |
60 |
57 |
1,4
|
| Qa |
8 |
7 |
9 |
7 |
12 |
18 |
|
| Qb |
10 (b+c) |
6 |
7 |
5 |
9 |
11 |
|
| Qc |
|
8 |
4 |
5 |
8 |
8 |
|
| R |
10 |
5 |
6 |
5 |
9 |
14 |
|
| SNARE total |
28 |
24 |
23 |
20 |
35 |
54 |
1,5,6
|
| NSF |
1 |
1 |
1 |
2 |
1 |
1 |
1,7
|
| SNAP |
1 |
1 |
1 |
3 |
1 |
3 |
|
| Sec1 |
5 |
4 |
6 |
5 |
7 |
6 |
8
|
Return to Top
Putative Sar and Arf genes from Entamoeba histolytica
Secretion-associated Ras-related (Sar) and ADP-ribosylation factor
(Arf) proteins are presented in the following table which includes:
Annotation, Protein Accession linked to
protein models (XP) linked to
NCBI's Entrez Protein database, mRNA models (XM) included in the
reannotation linked to TIGR's Annotation Display
(Pathema Annotation Link),
Nucleotide Accession linked to NCBI's
Entrez Nucleotide database, Number of Introns,
Proteins Length (aa), and Notes are presented.
Entamoeba histolytica Putative Sar and Arf Gene Annotation
Return to Top
Putative COPII, COPI, clathrin coat proteins and major binding
components from Entamoeba histolytica.
Entamoeba histolytica Vesicle Proteins
presented as Complex Name, Annotation, protein models
(XP) linked to NCBI's
Entrez Protein database (Protein Accession),
mRNA models (XM) included in the reannotation linked to TIGR's Annotation Display (Pathema Annotation Link),
or mRNA models not included in the reannoation linked to NCBI's
Nucleotide database (Models Excluded from the Reannotation), Nucleotide
Accession linked to NCBI's Entrez Nucleotide database and
Protein Length (aa).
Return to Top
Putative SNAREs and their accessory proteins from Entamoeba histolytica
Note: in the text of the Advances in Parasitology Review: Structure and Content of the Entamoeba histolytica
Genome (submitted), SNARE proteins are in section 6.3.
Footnote:
Please note that entries with ** have multiple Pathema Annotation Links.
Return to Top
